SAB BIO
Biotechnology
Miami Beach, Florida
Overall Rank: 57
Category: Biotechnology
Category Rank: 21
Awards:
Top Healthcare Technology Companies of 2024
Profile
SAB BIO (SAB) is a clinical-stage biopharmaceutical company whose lead asset, SAB-142, uses a disease-modifying therapeutic approach aiming to delay the onset of and potentially prevent disease progression of type 1 diabetes (T1D).
Through developing human, multi- targeted, high-potency immunoglobulins (IgGs), without the need for human donors or convalescent plasma, SAB looks to treat and prevent immune and autoimmune disorders, with a focus on T1D. Using advanced genetic engineering and antibody science to develop Transchromosomic (Tc) Bovine™, the only transgenic animal with a human artificial chromosome, SAB’s DiversitAb™ drug development production system can generate a diverse repertoire of specifically targeted, high-potency, human IgGs that can address a wide range of serious unmet needs in human diseases without the need for convalescent plasma or human donors.
Visit www.sab.bio
Key Products
SAB-142, a novel immunotherapy platform comprised of a human anti-thymocyte immunoglobulin (hIgG) intended to delay the onset or progression of type 1 diabetes.
Key Executives
- Samuel J. Reich, Chairman and CEO
- Eddie Sullivan, Ph.D., Co-Founder and President
- Christoph Bausch, Ph.D., MBA, EVP and Chief Operating Officer
- Dr. Alexandra Kropotova, MD, MBA, EVP and Chief Medical Officer
- Lucy To, Chief Finance Officer
Investors
NASDAQ: $SABS
Key Investor Partners:
- Sessa Capital
- BVF Partners
- RTW Investments
- Marshall Wace
- ATW
- T1D Fund
Competitors
- Vertex
- Provention Bio (acquired by Sanofi in 2023)
- Diamyd.
Corporate Responsibility
The chronic burden of type 1 diabetes is multifaceted, significantly affecting both physical and mental well-being. Managing symptoms and the risk of severe complications places a substantial strain on patients and caregivers. There is a clear and urgent need for treatment options that can delay the onset of type 1 diabetes or alter its disease trajectory. Efforts are focused on addressing this critical need and transforming the treatment paradigm for those affected by type 1 diabetes.

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